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This book is originally and especially dedicated to the students of Architecture Department at the University of Prishtina for Educational, and Not-for-profit purposes. The monograph incorporates contemporary knowledge of the Multimedia Studios - Architectural Design Principles, followed by research data, discussion, extracts, quotes and citations by various authors, as well as official government publications as the academic comparative references. Seeing the lack of literature in the field of Architecture, especially in the University of the Prishtina “Hasan Prishtina”, I was inspired by the research and writing this monograph, which elaborates the MultiMedia - Architectural Design Principles. The book is a free and not-for-profit purpose, it is intended as basic literature of Master courses which I taught at the University of Prishtina.

This year 2019 was wonderful as far as the purpose of our magazine is concerned. We were working together making visits to Schmelzeisen in Freiburg, Germany and preparing some changes in the Website. As you may have seen, now our readers are able to see the statistics with the exact number of views and downloads of every article. In the same way, we have added the option to filter all the articles according to the language you need just by clicking on the flags.

The topic of driving a car has typically focused on a person driving. The driver of a vehicle was and – to a large extent still is – required to possess the power to control all of the car’s functions. Recent technological and legal developments in the field of autonomous driving, however, demonstrate that the driver-centered principle in road traffic is beginning to lose relevance and in the future may become the exception or eventually disappear entirely. About the author: Dr. Hannah Dittmers studied law in Freiburg, Germany and Fribourg, Switzerland with a focus on private international law and European law. She obtained her LL.M. from the University of Michigan Law School in 2017 and her Ph.D. (Dr. jur.) from the University of Freiburg in 2019. She is currently a legal trainee (Rechtsreferendarin) at the Regional Court Freiburg.

Aim: The aim of our study was to assess the level and selected socio-demographic correlates of depression and anxiety among hospitalized adult patients in transitional Kosovo. Results: Mean summary score of the 16 items related to depression and anxiety level among hospitalized patients was 41.4±16.6; median score was 41 (interquartile range: 27-57). In multivariable-adjusted models, mean summary score of depression and anxiety level was higher among older patients, participants with low educational attainment, those with a low-income level, and individuals residing in urban areas. Conclusion: The study reveals a relatively high level of depression and anxiety among hospitalized adult patients in a major region of transitional Kosovo, especially among individuals pertinent to the low socioeconomic group. These findings should raise the awareness of policymakers and decision-makers in Kosovo in order to design appropriate strategies and implement effective programs.

The current issue of the Josha-Journal shows again the broad spectrum of topics our articles. You will read a contribution on a novel view of cancer and its microenvironment, a touching short story, new visions in architecture and town planning as well as reflections about the audience of classical music.

Dr. Bruce Gottlieb is the Project Director of the Lady Davis Institute for Medical Research at the Jewish General Hospital and Adjunct Professor of the Department of Human Genetics & Ingram School of Nursing at the McGill University in Montreal, Canada. This article belongs to one of his conferences and is an expanded abstract of his talk, to which he has added the most important references that he used at the conference. The approach of almost all current cancer therapies is essentially the same as those practiced by the Greeks and Romans, namely, to remove cancer tissues at a stage early enough to prevent cancer from overwhelming the body. While initial treatment regimens are often based on specific genomic data and are effective in many cases, they can sometimes be followed, usually after a period, by the reoccurrence of cancer as untreatable metastatic disease1, often with poor prognoses due to treatment resistance2.

Biophilia is the innately emotional affiliation of human beings to other living organisms. Biophilia, like other patterns of complex behavior, is likely to be mediated by rules of prepared and counter prepared learning. The significance of biophilia in human biology is potentially profound, even if it exists solely as weak learning rules. It is relevant to our thinking about nature, about the landscape, the arts. The biophilic design is not only the aesthetic perception, but those experiences may also be indicative of mental calmness and indirectly influence spiritually. The biophilic design focuses on human adaptations to the natural world. Featuring the natural organic structure, which transforms the perception and understanding of architectural buildings from exceptional one, into an honest and natural blend architecture, respectively, architectural biophilic design emphasizes the ‘genius loci’ an emotional attachment to particular settings and places. Cover Photo.

New in JOSHA: Publication statistics, more information, exceptional papers. This year 2019 was wonderful as far as the purpose of our magazine is concerned. We were working together making visits to Schmelzeisen in Freiburg, Germany and preparing some changes in the Website. As you may have seen, now our readers are able to see the statistics with the exact number of views and downloads of every article. Moreover, we have added three buttons on the right side of the Homepage, so you can get an option to visit our links directly to the upcoming events, to our prizes, and also see how you can become a member by clicking on the IASHA e.V. button. In another framework of ideas, we would like to remind you that you can immediately submit your work to participate in our Demetrios Prizes 2019. This time we are giving you again the opportunity to participate, to show to the world your researches and Ideas, and to win 500Euros.

Cardiovascular diseases and cancer are the most frequent causes of death in the industrialized world and their incidence increases significantly with age. Interestingly, autoimmunity is also seen with a higher frequency among older people. Is there a common pathogenic mechanism underlying this triad? One possible mechanism is the age-associated mutations that occur in all the cells of the human body capable of dividing. These mutations may lead to the formation of new proteins which can induce autoimmune reactions and inflammation that promote cancer and/or lead to an increased risk of cardiovascular disease. Here we review available evidence supporting the role of autoimmunity in the development of age-related diseases. If mutation-associated autoantibodies play a central role in the development of cardiovascular disease, cancer as well as neurological disorders, a new therapeutic option could be considered to switch off this key mechanism of the aging process.

Researchers have been interested in media and their impact on spoken and written language prior to the rise of the internet and Web 2.0. Plato already discussed the relationship between written and spoken language more than 400 BC. The chances that came with the beginning of digitalization are technical possibilities of detection, analysis, and evaluation of language. Academic disciplines such as linguistics and digital humanities are dedicated not only to dealing with digitalization and language but also to exploring their interrelationship, opportunities, and occurring (linguistic) phenomena. This paper critically questions Big Data practices in corpus linguistics research. I examine the Big Data corpus GloWbE (Corpus of Global Web-based English) as a linguistic research tool by highlighting advantages, emphasizing critical aspects, and presenting constructive approaches and concepts in the context of this paper.