Towards Simulating Carcinogenesis: Modeling and Simulating Carcinogenesis, Hematopoietic Tissue Homeostasis and Leukemogenesis
The previously identified cancer hallmarks (Groten et al. 2016, DOI: 10.17160/josha.3.7.252 ) were described by mathematical algorithms. Subsequently, a computational simulation of carcinogenesis has been developed. In the next step, the proposed algorithms and correlations have been tested, validated and adapted through the simulation (http://mertelsmann.psiori.com/). In a second model, we transferred the insights won from…