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2086 1719
Published in Volume 2, Issue 6 -

Post-Trial Obligations in the Declaration of Helsinki 2013

Ignacio Mastroleo

Languages: English

DOI: 10.17160/josha.2.6.65

Dr. Ignacio Mastroleo works on human health research ethics. Since Feb 2015 he is a member of the Post-Trial Responsibilities Workgroup of the Multi-Regional Clinical Trial (MRCT) Center, at Harvard University. He has a PhD in Philosophy from the University of Buenos Aires and Assistant Researcher at CONICET (National Scientific and Technical Research Council of Argentina) working at the Bioethics Program of FLACSO Argentina with his advisor, Dr. Florencia Luna. He was member of the research ethics committee at the Oncology Institute of the University of Buenos Aires. Last year he was awarded the Caroline Miles Scholarship of the Ethox Centre, Oxford University, UK and The Manuel Velasco Suarez Award for Excellence in Bioethics, by the Pan American Health Organization (PAHO) and the PAHO Foundation. In this presentation Dr. Mastroleone addresses the obligations of reserachers and clinicians after the formal clinical trial is completed.


6994 2443
Published in Volume 2, Issue 6 -

Informed Consent in Genomic Research: The Iterative Feedback Model

Felicitas Holzer

Languages: English

DOI: 10.17160/josha.2.6.64

Recently, there has been a discussion on the best way to implement informed consent for the disclosure of incidental findings in research using whole genome sequencing (WGS)/whole exome sequencing (WES) procedures. Appelbaum et al. (2014:29) present four different “prototypical models” for the return of incidental findings, drawing on a literature review on return of incidental findings, a survey of a large number of genomic researchers and in-depth interviews with researchers and genomic research participants. I agree with Appelbaum et al. (2014) that consent models could be evaluated with the ethical criterion of “consistency with researchers’ ethical obligations” which is based on the ethical principles “respect for persons, beneficence, and justice” stated in the Belmont Report (1979). However, I propose to draw a different conclusion than Appelbaum et al. from this ethical evaluation. Appelbaum et al.


6040 2773
Published in Volume 2, Issue 6 -

Genome Sequencing in Cancer Research and Therapy

Stefan Fröhling

Languages: English

DOI: 10.17160/josha.2.6.63

Stefan Fröhling has a long-standing interest in identifying genetic abnormalities that define disease subgroups and treatment outcome in patients with acute myeloid leukemia. Furthermore, he works to identify new cancer drug targets through a better understanding of the functional dependencies of hematologic and solid-organ malignancies, and to bring targeted approaches and molecularly based patient stratification to clinical trials and patient treatment broadly across tumor types.


2058 1576
Published in Volume 2, Issue 6 -

The Scientific, Social and Ethical Aspects of Prolonging Human Life

Christoph Borner

Languages: English

DOI: 10.17160/josha.2.6.62

Professor Borner is a leading scientist in the field of apoptosis research. His career and activities include the following stations: 2014-present Director of the International Master Program in Medical and Biological Sciences (IMBS) between the Universities of Buenos Aires and Freiburg 2013-present Professor and Tutor in Biology, Psychology and Environmental Sciences for the Business and Administration study track of the California Miramar University (CMU) in Nairobi, Kenya (50% lectures, 50% online/e-learning tutoring).


2681 1391
Published in Volume 2, Issue 6 -

Science, Ethics and Society: Introduction

Roland Mertelsmann

Languages: English

DOI: 10.17160/josha.2.6.61

Roland Mertelsmann is a haematologist and oncologist and was professor and chairman at the Freiburg University Medical Center, Department of Oncology and Hematology. Amongst others, Roland Mertelsmann is known for his scientific work in the fields of hematology, oncology and stem cell transplantation. He started his career as a medical student at the Universities of Göttingen, Hamburg and the King’s College School of Medicine, London. After his graduation at the University of Hamburg, he contributed to the isolation of the blood stimulating growth factor G-SCF during his work in Hematology and Clinical Oncology at Memorial Sloan-Kettering Cancer Center in New York. In 1985, he returned to Germany and became professor and head of the Department for Hematology and Oncology at the University of Mainz and since 1989 at the University of Freiburg. In 1994 he founded the philanthropic Biothera Foundation, which supports education, research and training in the Biomedical Sciences.


2443 1860
Published in Volume 2, Issue 6 -

International Congress of Translational Medicine- Announcement: Buenos Aires, Argentina, Nov 24-25, 2015

Christoph Borner, Cristina Arranz

Languages: English

DOI: 10.17160/josha.2.6.60

The Faculty of Pharmacy and Biochemistry (Facultad de Farmacia y Bioquímica) of the Universidad de Buenos Aires (UBA) hosts the second International Congress of Translational Medicine on November 24th and 25th . The event will be under the auspices of the German and Swiss Embassies in Buenos Aires. The International Congress will be held in the context of the International Master Program in Biomedical Sciences (IMBS) Cooperation, a German-Argentine Study Program at the Universities Freiburg and Buenos Aires which is currently being extended to the University of Montevideo, Uruguay. The Program was launched in 2008 and has already paved the way for many students who joined academic and professional careers after completing the Master Program. A broad range of topics in the fields of Molecular Biology and Medicine as well as Microsystems and Bioethics will be covered by the two day congress and communicated in oral and poster presentations. Dr.


2138 4313
Published in Volume 2, Issue 6 -

IMBS Class 2016-18: Inscription Open

Christoph Borner, Cristina Arranz

Languages: English

DOI: 10.17160/josha.2.6.59

In 2008 the International Master in Biomedical Sciences (IMBS) was established as a joint program between the Faculty of Medicine of the Albert Ludwigs University of Freiburg (ALU) and the Faculties of Medicine and Pharmacy and Biochemistry of the University of Buenos Aires (UBA) in Argentina. The aim of this program is to provide scientific knowledge and state-of-the-art experimental experience to current and emerging biomedical research areas with a focus on translational research and development. It is also meant to foster teaching and research cooperation between the two Universities and to contribute to cultural exchange on the master, PhD and professor level. The program was implemented in a specific agreement co-signed by the Rectors of the two Universities in 2008. Moreover, the cooperation was strengthened by the UBA visit of the Minister President of Baden-Württemberg Kretschmann in 2011 when another agreement was signed.


2598 1469
Published in Volume 2, Issue 5 -

JOSHA - Table of Contents Volume 2 Issue 5

Felicitas Holzer, Roland Mertelsmann

Languages: English

DOI: 10.17160/josha.2.5.58

We heartily welcome our readers to the new Issue 5 of Volume 2 in which we present the first part of the talks from the Bioethics Symposium “Science, Ethics and Society” which took place on 14th of August in Freiburg. Our special Issue guest is Florencia Luna, a bioethicist and researcher at CONICET (National Research Council Argentina) and FLACSO (Latin American Faculty of Social Sciences), Argentina, who addresses the topic of assisted reproductive technologies and points out some particular challenges of the technology in her talk “To say or not to say?”. A further special contribution to the Symposium and this Issue is the talk “Ethics in Epidemics and Disasters: Rights and Obligations of Healthcare Workers” by Andreas Reis from the World Health Organization, Geneva, Switzerland.


2240 1597
Published in Volume 2, Issue 5 -

Research Ethics in Epidemics and Public Health Emergencies

Felicitas Holzer

Languages: English

DOI: 10.17160/josha.2.5.56

Responses to epidemics, emergencies and disasters raise many ethical issues for the people involved, who include responders, public health specialists and policy-makers. This workshop provides an ethical view point on issues arising when research studies are conducted in these difficult contexts. In particular, it will be focused on adaptations of ethical oversight and processes, as deliberations of research ethics committees. Using the example of the recent Ebola outbreak in West Africa, the participants of the workshop will discuss ethical issues within a concrete case study. I would like to express my gratitude to Dr. Andreas Reis, WHO, and Dr. Ignacio Mastroleo, Universidad de Buenos Aires, for their continued support.


8401 3500
Published in Volume 2, Issue 5 -

Ethical Legal and Social Issues (ELSI) in Assisted Reproduction Technologies (ART)

Florencia Luna

Languages: English

DOI: 10.17160/josha.2.5.55

Florencia Luna received an M.A. from the University of Columbia (USA) and a Ph.D in philosophy from the University of Buenos Aires. She directs the Program of Bioethics and is teaching bioethics at FLACSO (Latin American University of Social Sciences). She is Principal Researcher at CONICET (National Scientific and Technological Research Council). She has been the President of the International Association of Bioethics (IAB) during 2003 to 2005. She is Temporary Advisor of the World Health Organization (WHO) since 1997 and is now Expert for WHO since 2009. She has been appointed to the Scientific and Technical Advisory Committee (STAC) of Tropical Disease Research (TDR) at WHO. Beginning in 2005, she became a member or the Steering Committee of the Global Forum on Bioethics in Research (GFBR). She is co- PI with Ruth Macklin of a research training grant of the Fogarty International Centre, NIH (National Institutes of Health- (US)) to train persons in ethics and research (2000-2016).