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2519 1408
Published in Volume 6, Issue 3 -

Can a Selection-Centric, Strengths-Based Approach to Cancer Treatment Help Treat or Prevent Cancer and Metastatic Disease?

Bruce Gottlieb

Languages: English

DOI: 10.17160/josha.6.3.546

Dr. Bruce Gottlieb is the Project Director of the Lady Davis Institute for Medical Research at the Jewish General Hospital and Adjunct Professor of the Department of Human Genetics & Ingram School of Nursing at the McGill University in Montreal, Canada. This article belongs to one of his conferences and is an expanded abstract of his talk, to which he has added the most important references that he used at the conference. The approach of almost all current cancer therapies is essentially the same as those practiced by the Greeks and Romans, namely, to remove cancer tissues at a stage early enough to prevent cancer from overwhelming the body. While initial treatment regimens are often based on specific genomic data and are effective in many cases, they can sometimes be followed, usually after a period, by the reoccurrence of cancer as untreatable metastatic disease1, often with poor prognoses due to treatment resistance2.


2803 2120
Published in Volume 6, Issue 3 -

Biomimicry and Biophilic Design: Multiple Architectural Precepts

Bujar Q. Bajçinovci

Languages: English

DOI: 10.17160/josha.6.3.544

Biophilia is the innately emotional affiliation of human beings to other living organisms. Biophilia, like other patterns of complex behavior, is likely to be mediated by rules of prepared and counter prepared learning. The significance of biophilia in human biology is potentially profound, even if it exists solely as weak learning rules. It is relevant to our thinking about nature, about the landscape, the arts. The biophilic design is not only the aesthetic perception, but those experiences may also be indicative of mental calmness and indirectly influence spiritually. The biophilic design focuses on human adaptations to the natural world. Featuring the natural organic structure, which transforms the perception and understanding of architectural buildings from exceptional one, into an honest and natural blend architecture, respectively, architectural biophilic design emphasizes the ‘genius loci’ an emotional attachment to particular settings and places. Cover Photo.


2371 1467
Published in Volume 6, Issue 2 -

Editorial Volume 6, Issue 2

María Fernanda Sandoval

Languages: English

DOI: 10.17160/josha.6.2.543

New in JOSHA: Publication statistics, more information, exceptional papers. This year 2019 was wonderful as far as the purpose of our magazine is concerned. We were working together making visits to Schmelzeisen in Freiburg, Germany and preparing some changes in the Website. As you may have seen, now our readers are able to see the statistics with the exact number of views and downloads of every article. Moreover, we have added three buttons on the right side of the Homepage, so you can get an option to visit our links directly to the upcoming events, to our prizes, and also see how you can become a member by clicking on the IASHA e.V. button. In another framework of ideas, we would like to remind you that you can immediately submit your work to participate in our Demetrios Prizes 2019. This time we are giving you again the opportunity to participate, to show to the world your researches and Ideas, and to win 500Euros.


3839 1445
Published in Volume 6, Issue 2 -

Unraveling the syndrome of the age-associated diseases: Cancer, Cardiovascular, and Neurological disorders. Common pathways and novel therapeutic strategies

Laura Faletti, Roland Mertelsmann, Katja Zirlik

Languages: English

DOI: 10.17160/josha.6.2.539

Cardiovascular diseases and cancer are the most frequent causes of death in the industrialized world and their incidence increases significantly with age. Interestingly, autoimmunity is also seen with a higher frequency among older people. Is there a common pathogenic mechanism underlying this triad? One possible mechanism is the age-associated mutations that occur in all the cells of the human body capable of dividing. These mutations may lead to the formation of new proteins which can induce autoimmune reactions and inflammation that promote cancer and/or lead to an increased risk of cardiovascular disease. Here we review available evidence supporting the role of autoimmunity in the development of age-related diseases. If mutation-associated autoantibodies play a central role in the development of cardiovascular disease, cancer as well as neurological disorders, a new therapeutic option could be considered to switch off this key mechanism of the aging process.


3065 2057
Published in Volume 6, Issue 2 -

Evaluation of GloWbE as a Tool for Big Data Corpus Linguistics

Philipp Reichenbach

Languages: English

DOI: 10.17160/josha.6.2.538

Researchers have been interested in media and their impact on spoken and written language prior to the rise of the internet and Web 2.0. Plato already discussed the relationship between written and spoken language more than 400 BC. The chances that came with the beginning of digitalization are technical possibilities of detection, analysis, and evaluation of language. Academic disciplines such as linguistics and digital humanities are dedicated not only to dealing with digitalization and language but also to exploring their interrelationship, opportunities, and occurring (linguistic) phenomena. This paper critically questions Big Data practices in corpus linguistics research. I examine the Big Data corpus GloWbE (Corpus of Global Web-based English) as a linguistic research tool by highlighting advantages, emphasizing critical aspects, and presenting constructive approaches and concepts in the context of this paper.


2350 1409
Published in Volume 6, Issue 2 -

“If You Speak It, You Play It”

Ugo Rodolico

Languages: English

DOI: 10.17160/josha.6.2.536

The central idea of my thesis is to establish a close relationship between specific drumming technique, which is based today on the study of the rudiments seen earlier, and a more general method of learning rhythm that uses strategies and suggestions from outside classical music theory, which is understood solely as a division system. The Greeks described rhythm with words that always point to a deep relationship between movement and the temporal arts. The fundamental distinction has always been between arsis and thesis, that is, between momentum and support. The original meaning of these two words had to do with the alternating struggle of all movements of the body against gravity; momentary impulses always followed by relapses and supports that originated new impulses.


2273 1889
Published in Volume 6, Issue 2 -

Interactive Kinetic Architecture: Progressive Design Principles

Bujar Q. Bajçinovci, Vlora Aliu, Bard Bajçinovci, Uliks Bajçinovci

Languages: English

DOI: 10.17160/josha.6.2.535

Interactive architecture encompasses building automation but goes beyond it by including forms of interaction engagements and responses that may lay in pure communication purposes as well as in the emotive and artistic realm, thus entering the field of interactive art. In the coming decades, a new interactive architecture process will continue to be largely implemented into the urban-architectural environment. Various performative art media also embark on interactive architectural design strategies. Therefore, the combination of sensors, processors, and effectors of the variable elements in the architectural structure transforms the perception and understanding of the architectural buildings from passive one into an active evolutive composition.


1922 1354
Published in Volume 6, Issue 1 -

Editorial Volume 6, Issue 1

María Fernanda Sandoval

Languages: English

DOI: 10.17160/josha.6.1.534

The first month of 2019 has been very stimulating, check the " News &Views" section on the left side of our homepage. We have been visiting and working with prestigious artists and musicians including video interviews and reports. In addition, we have published a number of important articles in the fields of Medicine, Architecture, among others, covering the spectrum of sciences, humanities, and arts. We are also constantly improving our Website for you. Now articles can be classified into more than one category. Furthermore, also videos may be added to your articles as a link. To watch press the button “Watch Video” at the bottom of the respective article. You may also select articles by sections such as Medicine etc. on the left side of the homepage. Furthermore, you may select articles by language and search words of your choice. Shortly, the statistics of each article will be available to our readers, covering the time since October 2019.


2322 1425
Published in Volume 6, Issue 2 -

3D printed scaffold to monitor hanging drops on inverted microscopes

Lukas Peintner

Languages: English

DOI: 10.17160/josha.6.2.531

Growing cells in 3D cell culture became a major field in cell biology over the last decade. Cells growing in a dimensionally unrestricted space spontaneously form organoids or spheroids that express cellular behavior different from cells growing on a plane surface. However, monitoring three dimensional spheroids on standard inverted microscopes proved difficult since hanging drops are often outside the focus range. Here I present the design and production of a cover slip tray by conventional additive printing (3D printing) able to fit into a single well of a six-well plate to enable the observation of hanging drop spheroids using inverted microscopes.


1998 2026
Published in Volume 6, Issue 1 -

Emergency Reconstruction of Primary Schools in post-conflict context: the case of Kosovo

Vlora Navakazi, Bardha Meka, Flaka Xerxa

Languages: English

DOI: 10.17160/josha.6.1.530

The post-war situation in Kosovo after 1999, in most cities and especially in rural settlements, was immensely difficult due to completely or partially burned public facilities, among which, school buildings suffered the most. To recover such a state, emergency interventions from many international organizations besides reconstruction of residential buildings being the priority of the programs were mainly focused in the improvement of the primary school buildings’ infrastructure, as it was an important factor to return residents in their settlements. The purpose of this study is to analyze the process of emergency design and construction of primary schools in the post-war period in Kosovo, from 1999 and afterward, also to investigate the impact of the used standards on the reforming of the educational system.